Position Overview

  • 3 Year Fixed Term | Full Time | $107k - $138k +15.4% super
  • Lucas Heights, NSW location | Flexible Work practices I Health & Wellbeing Programs
  • Exciting and challenging opportunity to contribute to the establishment of synthetic biology capability at ANSTO’s National Deuteration Facility (NDF) for engineering the biosynthetic production, purification and characterisation of organic molecules labelled with stable isotopes (2H, 13C, 15N).
  • Great opportunity to be part of the NDF which is the only facility of its kind in Australia and one of only few in the world.

About the Opportunity

The National Deuteration Facility seeks a motivated and driven Biochemist/Molecular Biologist to utilise microbial genomes in design-build-test-learn cycles to produce new candidate molecules and provide scale-up production and purification capability. This opportunity will allow you to develop new target systems for biosynthetic production of purified stable isotope labelled molecules while making substantial contributions to research, industry engagement, and outreach efforts.

The NDF Biochemist will lead the synthetic biology effort to design and build new microbial strains for biosynthesis of desired molecules, to complement the organic chemistry output. The role will also be responsible for developing small scale expression and purification protocols, and scale-up production and purification for supply of labelled molecules to users. Reporting to the NDF Director, the role has significant input into development of new research activity and grant opportunities for the NDF.

About You

In this role, you will establish the synthetic biology platform for developing new strains capable of producing bespoke labelled molecules. You will have expertise in molecular techniques for heterologous expression in microbial systems, and in the purification and characterisation of organic molecules.

We are looking for a highly motivated and talented biochemist with demonstrated research experience in synthetic biology Design-Build-Test-Learn systems who is eager to contribute to groundbreaking discoveries in scienceProf. Tamim Darwish - Director of the National Deuteration Facility.

Your Duties and Responsibilities

  • Development of new protocols for production and purification of stable isotope labelled lipids and other molecules using synthetic biology principles.
  • Perform genome mining to identify genes for development of new biosynthetic pathways and bioproduct synthesis.
  • Use bioreactor screening techniques with design-build-test-learn cycles to develop strains for efficient production of labelled molecules.  
  • Perform sequencing and data analysis to characterise new microbial strains, providing a library of candidate strains for new target molecules.
  • Develop small scale expression and purification protocols and perform scale-up production and purification for supply of labelled molecules to users.
  • Establish networks with external researchers undertaking investigations that would benefit from the use of stable isotope labelled molecules.
  • Supervise research students and provide expertise in the use of instruments and protocols.


Please click here to view the Position Description.

About Us

ANSTO leverages great science to deliver big outcomes.  We partner with scientists and engineers and apply new technologies to provide real-world benefits.  Our work improves human health, saves lives, builds our industries and protects the environment.  ANSTO is the home of Australia's most significant landmark and national infrastructure for research.  Thousands of scientists from industry and academia benefit from gaining access to state-of-the-art instruments every year.

Benefits of Working with Us

ANSTO employees are passionate about what they do. We enjoy being part of an organisation making a difference in the lives of Australians. 

We support and reward our employees through eligibility for:

  • Training, development and mentoring opportunities 
  • Performance based salary increases 
  • Work-life balance with generous leave entitlements and flexible conditions


If you want to join a world class organisation that's making a difference in the lives of Australians, apply now!

How to Apply

For further technical information relating to this position please refer to the Position Description or contact Tamim Darwish on (02) 9717 9080.  For all other queries please contact Talent Acquisition on +61 (02) 9717 3740


To be eligible for appointment, applicants will require a security and pre-employment medical assessment.


Application closing date:  28 May 2024 at 11:59pm





In order to solve great challenges, we need great minds and great teams. At ANSTO, we understand that diverse teams produce better outcomes and we value the merit that a diverse perspective can bring to our team. We encourage people from diverse backgrounds to apply for our roles including Aboriginal and Torres Strait Islander people, primary carers, those with a disability, and women in STEM. ANSTO is a charter member of the Science in Australia Gender Equity (SAGE) initiative and is proudly taking action to create a gender-inclusive workforce.