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Medicinal Chemist - Mass Spectrometry

Position Overview


  • Fixed Term - 2 Years | Full Time | $118k - $132k +15.4% super 
  • Possible term extension
  • Work in a unique deuteration facility; one of very few in the world and the only one in the southern hemisphere. 

About the Opportunity


The Medicinal Chemist – Mass Spectrometry is responsible for the maintaining and operating the NDF’s Liquid Chromatography (LC) and Gas Chromatography (GC) -Mass Spectrometer (MS) systems and manages the associated workflow and research activities utilising these instruments.  You will provide subject matter expertise to NDF staff and external users, including industry, for MS analysis of small organic molecules in biological applications (e.g., pharmaceutical, healthcare products) as well as  troubleshoot high complexity MS analyses of other molecule classes already undertaken by existing staff.

About You


"We are looking for a highly skilled medicinal chemist with demonstrated expert level range of mass spectrometry techniques including all aspects of MS operation, interpretation of spectra, quantitative analysis and validation of methodology. The successful applicant will be utilising their medicinal or synthetic chemistry background to lead the design of bio-analysis MS studies of deuterated compounds in biochemical applications." - Dr Tamim Darwish, Leader- National Deuteration Facility

Your Duties and Responsibilities


  • Provide scientific leadership and expert knowledge to ensure the effective development and deployment of deuterium labelling in medicinal chemistry for mass spectrometry applications.
  • Provide scientific expertise in LC-MS/MS and GC-MS analysis of deuterated molecules and their kinetic isotope effect in medicinal chemistry as analysed by MS techniques.
  • Design and execute experiments to profile metabolomic content of deuterated samples using GC-MS and LC-MS.
  • Conduct routine production of deuterated molecules, evaluate, validate and execute new and improved production methods for supply to MS and medicinal chemistry users.  
  • Present and summarise scientific findings in reports and presentations, and prepare and submit manuscripts to peer-reviewed scientific journals for publication.


Please click here to view the Position Description.

About Us


ANSTO leverages great science to deliver big outcomes.  We partner with scientists and engineers and apply new technologies to provide real-world benefits.  Our work improves human health, saves lives, builds our industries and protects the environment.  ANSTO is the home of Australia's most significant landmark and national infrastructure for research.  Thousands of scientists from industry and academia benefit from gaining access to state-of-the-art instruments every year.

Benefits of Working with Us


ANSTO employees are passionate about what they do. We enjoy being part of an organisation making a difference in the lives of Australians. 

We support and reward our employees through eligibility for:

  • Training, development and mentoring opportunities 
  • Performance based salary increases 
  • Work-life balance with generous leave entitlements and flexible conditions


If you want to join a world class organisation that's making a difference in the lives of Australians, apply now!

How to Apply


For further technical information relating to this position please refer to the Position Description or contact Tamim Darwish on +61 2 9717 9080.  For all other queries please contact Talent Acquisition on +61 (02) 9717 3359.


To be eligible for appointment, applicants will require a security and pre-employment medical assessment.


Application closing date:  30 January 2022


All applicants must be Australian citizens.



In order to solve great challenges, we need great minds and great teams. At ANSTO, we understand that diverse teams produce better outcomes and we value the merit that a diverse perspective can bring to our team. We encourage people from diverse backgrounds to apply for our roles including Aboriginal and Torres Strait Islander people, primary carers, those with a disability, and women in STEM. ANSTO is a charter member of the Science in Australia Gender Equity (SAGE) initiative and is proudly taking action to create a gender-inclusive workforce.